Repeat yourself if necessary. Be polite and efficient. You should start with something that they can answer easily. Don’t inquire as to how they are if you think they’ll take it seriously. When I was younger, I would write down a list of five questions, starting from specific to broader to controversial if applicable. You want to start a conversation, not a fugue in three parts. Writing down the list helps you identify which topics you want to discuss and which ones you don’t. Make sure you’re always to the point and don’t be afraid to clarify. Does what I’m saying make sense?
Don’t ask stupid things. “If you were a fruit, what type would you be?” is only relevant when auditioning for grocery commercials or certain children’s plays. Get to the point but with as much respect or lack thereof as they deserve. If they wander and you don’t want them to, leash them in when they pause for breath: “I see. But going from before…” Repeat yourself if necessary. It is your responsibility to assume control, even if they’re the boss. But don’t cut them off if they’re giving what you want but not what you expected. The most recent interview I did saw the talent spend more than half his time answering my first question. You want to start a conversation, not end one prematurely. Ask questions which give your talent open space to shine. Why would you do that?
Questions work both ways. If you’re the talent, make sure you’re always to the point and don’t be afraid to clarify. The “any questions?” stage of a job interview is a chance for you to turn inquisitor and assume the privilege of need-to-know usually held by journalists and spies. I have never sat for a job interview. Keep things spontaneous and if the conversation meanders downstream, go with the flow but don’t use silly metaphors. Be efficient, and polite, even if they turn hostile. In case of emergency, slap their common-sense until it bleeds. What’s the difference between a duck?